BRAIN-HR SCIENCE SUITE · 3 RESEARCH PLATFORMS WITH DETERMINISTIC COMPUTE KERNELS
Deterministic compute kernels and full data sovereignty for frontier research and teaching.
In medical and psychological evidence synthesis, university neuroanatomy teaching, and bioinformatics, a language model must never guess statistics in its head or transmit sensitive raw data externally. Our three Science and Deep-Tech platforms unite verified primary literature, isolated compute kernels, and 100% local data sovereignty.
- 01MetaAnalysis Studio: 4-Gate Research Cockpit, 🎓 Student Mode & 11-Tab Professor Studio with blinded dual-house screening, isolated R compute kernel (metafor/CR2) & 29-part package.
- 02Encephalon Studio: Complete interactive 3D brain atlas with 3,539 structures (DE/EN/LA), 5 discovery trees, 970 study cards, PET/EEG/TMS/DBS labs & local MRI viewer.
- 03SNP Browser (RUO): Local zero-egress genomics workbench for 80 GB BAM/CRAM/VCF with htslib streaming, 289 NIST-GIAB-calibrated loci, 46 pharmacogenes & plink2 pipeline.
Executive Overview (1:41 min): How MetaAnalysis Studio, Encephalon Studio, and SNP Browser (RUO) unite deterministic compute kernels, calibrated reference atlases, and local data sovereignty.
SCIENTIFIC PRECISION INSTEAD OF BLACK-BOX AI · THE 3 ARCHITECTURAL GUARANTEES
What separates our three research platforms from generative language models.
When peer review, clinical lectures, or genomic cohort analyses are on the line, deterministic verification replaces every statistical guess from a language model.
R (metafor/CR2), 0.5 mm MNI152 Catalog & C-htslib/plink2
Zero math inside the language model: MetaAnalysis Studio computes in an isolated R kernel, Encephalon Studio locks every camera flight against 3,539 MNI152 structures, and the SNP Browser runs C-htslib and plink2 down to machine precision.
PDF Page Proofs, 19 PET Cohorts & NIST-GIAB Calibration
Every extracted study number carries its verbatim PDF page proof; every brain structure links to 1,279 primary studies and 19 human PET cohorts; all 289 genomic loci are calibrated base by base against NIST-GIAB (HG001–HG007).
Blinded Dual-House Screening & 100% Local Data Sovereignty
Two independent frontier models (Claude Opus 5.5 & GPT-6.1 Sol) screen studies in a blinded dual-house workflow, while your own MRI/DICOM scans and 80 GB genomic files never leave your local machine.
MetaAnalysis Studio: From the 4-Gate Research Cockpit and R compute kernel to the 29-part submission package.
MetaAnalysis Studio unites the guided 4-Gate Research Cockpit and didactic 🎓 Student Mode with the full methodological control of the 11-Tab Professor Studio. Search over 250 million works live, delegate screening to two blinded frontier models, and run all statistical models inside an isolated R compute kernel.
- ✓ Global PRISMA-S Search & Blinded Dual-House Screening: OpenAlex, PubMed & ClinicalTrials.gov; blinded screening by Claude Opus 5.5 & GPT-6.1 Sol
- ✓ Isolated R Compute Kernel (metafor & clubSandwich CR2): Three-level models, survival & network meta-analyses, 5-fold publication bias testing
- ✓ Science Transfer & Verifiable Proofs: Plain-language translation (CLES), verbatim PDF page proof for every extracted figure, and open calculation ledger
- ✓ Co-Editor with Number Guardian & 29-Part Export: Word/PDF manuscript, forest/funnel vector graphics, standalone R reproduction script & conference poster
Six stations: 4-Gate Research Cockpit, blinded dual-house screening, R compute kernel (metafor/CR2), plain-language translation, PDF page proofs & 29-part package.
Encephalon Studio: 3,539 brain structures in 3D, PET/EEG labs, clinical simulation & AI Director Cockpit.
Encephalon Studio bridges accessible introduction and advanced university teaching, clinical practice, and research: explore 3,539 anatomical structures and real fiber tracts trilingually in 3D, connected with five discovery trees, 970 study cards (1,279 primary studies), eight specialized simulation labs, a local MRI viewer, and the AI Director Cockpit.
- ✓ 3,539 3D Structures & 5 Discovery Trees: Classical anatomy, Brodmann areas & functional networks (Yeo & Schaefer) with 970 study cards
- ✓ Human PET Receptor Atlases & 3D Electrophysiology: 19 original cohorts with live pharmacodynamics plus EEG, sLORETA & neurofeedback
- ✓ Clinical Simulation: 10 disorder models in before/after comparison, stroke across 7 vascular territories, plus TMS/tES & Deep Brain Stimulation (DBS)
- ✓ Local MRI/NIfTI/DICOM Viewer & Director Cockpit: Overlay your own scans without upload and export guided 3D tours as HD videos
Five stations: 3,539 3D structures, 5 discovery trees & 970 study cards, PET/EEG labs, disorder & TMS/DBS simulation, local MRI viewer & AI Director Cockpit.
SNP Browser (RUO): Calibrated local research workbench for genomics, pharmacogenomics & cohort PGS.
Instead of chaining together six separate command-line tools for alignment streaming, coordinate liftover, haplotyping, polygenic scoring, and literature synthesis, the SNP Browser unites the entire pipeline inside a locally air-gapped zero-egress workbench (exclusively for demonstrably qualified research personnel / RUO).
- ✓ In-Place htslib Byte-Range Streaming & Pileup Viewer: Analyze 80 GB BAM/CRAM/VCF without file copying; 289 loci calibrated against NIST-GIAB (HG001–HG007)
- ✓ 28 Specialist Panels, 46 Pharmacogenes & 40 Composite Rules: Deterministic resolution following CPIC/PharmVar plus local ClinVar & ACMG scanner
- ✓ Integrated plink2 Pipeline on 1000 Genomes Reference Data: Single samples & multi-sample cohorts with strict separation (Missing != Wildtype)
- ✓ Zero-PII Literature Federation & AES-256-GCM Dossier: Simultaneous rsID extraction across PubMed, Europe PMC, OpenAlex & Crossref
Five stations (Research Use Only): In-place htslib streaming, 289 NIST-GIAB-calibrated loci, 28 specialist panels & 46 pharmacogenes, plink2 pipeline, and zero-PII literature federation.
FIRST THEMATIC SUITE · L&D & CORPORATE EDUCATION APPS (3 TOOLS)
Responsible for corporate training, leadership development, or a corporate academy?
On our L&D Suite page, explore our three specialized corporate education and consulting tools with their own Hero walkthrough video: Evidence Check (method and vendor auditing), Learning Design Studio (seminar construction & Constructive Alignment audit), and BRAIN-HR LMS / Digital Learning Space (white-label academy with workplace transfer).
Personal architecture and benchmark walkthrough (25 minutes, free of charge).
Bring your current research question, your lecture topic, or your institutional requirements for a local research workbench. We demonstrate the platforms live on official reference datasets.
Schedule a research walkthrough →